Dr Lee is a renal physician at Westmead Hospital and is Subdean (Medicine) of the Western Clinical School, Sydney Medical School of the University of Sydney. He graduated in medicine from the University of Sydney with first class honours in 1995, and received his fellowship of the Royal Australasian College of Physicians in 2004. He was awarded his PhD in 2010 for studies into the pathogenesis of tubulointerstitial injury in chronic kidney disease
His current research aims to deliver better health care to people with chronic kidney disease, and focussed interests include the use of novel technologies to improve dietary and lifestyle behaviour in people with CKD, dialysis, AKI, preeclampsia and the impacts of CKD in pregnancy. He is also conducting his lab research on the immunological mechanisms of chronic kidney disease progression, and the role of inflammation in vascular calcification and preeclampsia.